研究揭示细菌何以产生抗药性

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         UK - Scientists from the Institute of Food Research and the University of East Anglia have discovered how certain gut bacteria can protect themselves and others in the gut from antibiotics.

         The bacteria produce compounds, called cephalosporinases, which inactivate and destroy certain antibiotics such as penicillin derivatives and cephalosporins, protecting themselves and other beneficial bacteria that live in close proximity. However, they may also give protection from these antibiotics to harmful bacteria, such as Salmonella.

         The gut is home to hundreds of trillions of bacteria, which have important roles in maintaining our health. But a side effect of taking antibiotics is that these may also kill off some of our beneficial gut bacteria, allowing harmful bacteria to gain a foothold and cause an infection.

      英国——来自食品研究所和东安格利亚大学的科学家发现,某些肠道细菌如何保护自己和在肠道内的其他细菌,免受抗生素的影响。

      这些细菌产生称为cephalosporinases的化合物,此化合物钝化并摧毁某些抗生素,如青霉素衍生品和头孢菌素,保护自己和其他有益的生活在附近的细菌。然而,它们也可能保护有害细菌,免受抗生素的影响,如沙门氏菌。

      肠道中生活着数以万亿计的细菌,它们对维护我们的健康有重要的作用。但服用抗生素后,其副作用也可能杀死一些对我们肠道有益的细菌,让有害细菌站稳脚跟并导致感染。    


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